More info on Berberine (BBR). This data is from an article we co-published in 2012 on fat reduction, glucose lowering, and increased mitochondrial activity in rats fed with 100ย mg BBR/kg weight/day in water. Look at the 3rd column. sciencedirect.com
Note that you can't just convert weight:weight from rats to humans. There's what's called allometric scaling. Divide rat dose by 6.2. For mice its 12.3. ncbi.nlm.nih.gov
Berberine is a plant alkaloid with a long history of use in both Ayurvedic and Chinese medicine. It tastes super bitter and is bright yellow. I swallow it without ever letting the capsules open ๐คข
Free review on Berberine and effects on metabolism in humans: frontiersin.org
If you buy a supplement, be sure to look for "GMP" on the label and look up what the pure compound should look like e.g. Pubchem has info: Berberine, "Yellow solid". If it's different, throw it away ๐ฎ #section=Experimental-Properties" target="_blank" rel="noopener" onclick="event.stopPropagation()">pubchem.ncbi.nlm.nih.gov
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