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MEAN PLATELET VOLUME (MPV)
I posted a poll last week asking whether you use MPV in your clinical practice. No right answer here! Most (61.5%) answered NO, that MPV is not helpful.
I did a deep dive and arrived at the following conclusions:
MEAN PLATELET VOLUME (MPV)
I posted a poll last week asking whether you use MPV in your clinical practice. No right answer here! Most (61.5%) answered NO, that MPV is not helpful.
I did a deep dive and arrived at the following conclusions:
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1. MPV is automatically generated by virtually all modern hematologic analyzers as part of the CBC.
2. However, the MPV is not always provided to clinicians at point of care because of concerns about lack of standardization and clinical relevance.
1. MPV is automatically generated by virtually all modern hematologic analyzers as part of the CBC.
2. However, the MPV is not always provided to clinicians at point of care because of concerns about lack of standardization and clinical relevance.
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3. There are three areas of clinic interest with MVP:
3a. Distinguishing whether thrombocytopenia is due to peripheral destruction of platelets or increased destruction of platelets.
3. There are three areas of clinic interest with MVP:
3a. Distinguishing whether thrombocytopenia is due to peripheral destruction of platelets or increased destruction of platelets.
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3b. Distinguishing whether thrombocytopenia is due to ITP or inherited macrothrombocytopenias.
... although the MVP may be helpful for differentiating between different causes of thrombocytopenia, it has insufficient discriminatory power to be definitive on its own.
3b. Distinguishing whether thrombocytopenia is due to ITP or inherited macrothrombocytopenias.
... although the MVP may be helpful for differentiating between different causes of thrombocytopenia, it has insufficient discriminatory power to be definitive on its own.
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3c. Population-level studies demonstrating an association between MPV and the diagnosis and prognosis of thrombotic diseases (without thrombocytopenia).
Unanswered question:
Does high MVP predispose to thrombosis (i.e., is it causative) or does thrombosis cause high MVP?
3c. Population-level studies demonstrating an association between MPV and the diagnosis and prognosis of thrombotic diseases (without thrombocytopenia).
Unanswered question:
Does high MVP predispose to thrombosis (i.e., is it causative) or does thrombosis cause high MVP?
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... the value of the MPV in diagnosing and prognosticating at the level individual patients with these thrombotic conditions is unclear.
See tutorial: thebloodproject.com
... the value of the MPV in diagnosing and prognosticating at the level individual patients with these thrombotic conditions is unclear.
See tutorial: thebloodproject.com
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