8 Tweets 4 reads Jan 19, 2024
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Constipation
We have all experienced it.
Viewed as a benign diagnosis (though not benign to the person experiencing it).
You need to know when it is not a "benign" diagnosis but rather a proximal clue to a sinister diagnosis.
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During 28-hour calls in the hospital, I definitely experienced constipation, likely reflecting my lack of fluid intake. And trust me it was not benign to me though increasing fluid intake resolved this problem.
ncbi.nlm.nih.gov
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Red flags that should prioritize a secondary etiology as opposed to a functional cause include
🫵Acute onset without prior history
🫵Inflammation
🫵Iron deficiency anemia (? 2/2 colon cancer)
🫵Neuro symptoms (? 2/2 myelopathy or cauda equina syndrome)
🫵Obstructive symptoms (? 2/2 colon cancer)
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1st step is to review meds for iron, opioids, or anticholinergics
Tests to order in most
🫵CBC (look for anemia, if present then iron studies)
🫵Comprehensive metabolic panel (look for hyperglycemia, hypercalcemia, hypokalemia)
🫵TSH (look for hypothyroidism)
Other tests based on unique findings
+/- CT-abd/pelvis (acute onset, obstructive signs)
+/- Colonoscopy (iron deficiency)
+/- MRI (neuro findings)
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No red flags then likely dealing with/ an idiopathic or functional cause of constipation like slow transit defecation, dyssynergic defecation, or IBS-C (+/- mild abdominal pain)
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Complications of constipation?
Fecal impaction → incresed pressure of mucosal wall → decreased blood -> stercoral ucler → bleeding +/- anemia and/or perforation
Straining → hemorrhoids, anal fissure
Sigmoid volvulus
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In summary
🫵no symptom is ever benign to the person who has the symptom
🫵need to know when constipation is likely a proximal clue to a secondary (nonfunctional) cause
🫵constipation independent of its etiology can lead to complications
Study this amazing figure created by the greatest schema creator of all time @rabihmgeha
clinicalproblemsolving.com
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BTW what prompted this thread is a soon-to-be-released RLRCPSolvers.com episode. We tackle bread and butter with the hope of promoting excitement for clinical reasoning and better patient care through higher diagnostic accuracy.

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