๐—ก๐—ถ๐—ต๐—ฎ๐—ฟ ๐——๐—ฒ๐˜€๐—ฎ๐—ถ MD, DM
๐—ก๐—ถ๐—ต๐—ฎ๐—ฟ ๐——๐—ฒ๐˜€๐—ฎ๐—ถ MD, DM

@nihardesai7

10 Tweets 9 reads Aug 22, 2023
Hey #medicine residents !!
PLEASE TRANSFUSE BLOOD PRODUCTS JUDICIOUSLY ๐Ÿ™๐Ÿป
Not every patient with anemia needs blood and not is blood transfusion free of complications.
I'll list out a few TRANSFUSION REACTIONS in case you'll have forgotten about them ๐Ÿ‘‡๐Ÿป
#MedTwitter
1/10
Let's start w/ TACO๐ŸŒฎ
This isn't the good Mexican ๐ŸŒฎ we love๐Ÿคฃ
This is pulmonary oedema resulting from overzealous transfusion๐Ÿคทโ€โ™‚๏ธ
Risk factors: patients who can't handle fluids we'll, i.e. patients w/ kidney,heart disease etc
Totally avoidable complication๐Ÿ™๐Ÿป
#MedTwitter
2/10
A close differential of TACO is TRALI. The symptoms are the same but this is non-cardiogenic pulmonary oedema.
So BNP will be normal here, neck veins won't be dilated
TACO needs diuretics and some restraint on your part๐Ÿคฃ
TRALI=supportive care
#MedTwitter
3/10
These are bad, but the worst is acute hemolytic transfusion reactions ๐Ÿ˜ญ๐Ÿ˜ญ
Can be fatal if not recognised & managed immediately๐Ÿ˜ณ
Clinically: fever, dyspnoea, flank pain, red urine
All because of intravascular hemolysis & most often due to mismatched group transfusion๐Ÿ˜ญ
4/10
It's less evil twin is DELAYED HEMOLYTIC TRANSFUSION REACTION
This is d/t alloimmunization & is more often seen in heavily transfused pts.
Occurs a week or so after transfusion, is IgG mediated (rarely complement) so p/w features of EXTRAVASCULAR HEMOLYSIS !
#MedTwitter
5/10
There's another common reaction we see very frequently๐Ÿ˜ญ
FEBRILE NON-HEMOLYTIC TRANSFUSION REACTION (FNHTR)
This is d/t anti-leucocyte antibodies and is minimised if leucodepleted blood products are used.
P/w fever but no signs of hemolysis๐Ÿ™๐Ÿป
Needs some supportive care.
6/10
This is obviously over and above the numerous INFECTIOUS COMPLICATIONS one can encounter !!
Hep B
Hep C
HIV
HTLV
CMV
Parvo
And rarely bacterial sepsis ๐Ÿ˜ญ๐Ÿ˜ญ๐Ÿ˜ญ
#MedTwitter
7/10
Also, every unindicated transfusion takes up valuable nursing time.
Blood banks work hard to give you the product, help them out by saying NO to inadvertent transfusions ๐Ÿ™๐Ÿป
Your reaction to unindicated transfusion must be ๐Ÿ‘‡๐Ÿป
8/10
I don't think I need to remind you how blood banks obtain blood ๐Ÿคทโ€โ™‚๏ธ
It's not from Pharma but from donors like you and me. It's a precious resource, DON'T WASTE IT.
#MedTwitter
9/10
Thanks for reading this far ๐Ÿซก๐Ÿซก
I hope you'll stop and question yourself before you recommend the next transfusion ๐Ÿ™๐Ÿป
#MedTwitter
End.

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