Weekend Digest
Name the Pathogen
Five Clues:
1. Gram-negative bacillus
2. Healthcare-associated pneumonia and bloodstream infections
3. Exposure to natural disasters in the tropics
4. Siderophore
5. Multi-drug resistance; intrinsic resistance to aztreonam
Name the Pathogen
Five Clues:
1. Gram-negative bacillus
2. Healthcare-associated pneumonia and bloodstream infections
3. Exposure to natural disasters in the tropics
4. Siderophore
5. Multi-drug resistance; intrinsic resistance to aztreonam
2/
#Acinetobacter spp., most commonly baumannii
The other suggested answers are:
#Burkholderia
#Elizabethkingia
#Pseudomonas
#Stenotrophomonas
But the clue โinfections associated with (man-made and natural) disasters in the tropicsโ is alluding to Acinetobacter.
#Acinetobacter spp., most commonly baumannii
The other suggested answers are:
#Burkholderia
#Elizabethkingia
#Pseudomonas
#Stenotrophomonas
But the clue โinfections associated with (man-made and natural) disasters in the tropicsโ is alluding to Acinetobacter.
3/
#Acinetobacter infections is common in #tropical countries.
Acinetobacter is a common cause of nosocomial pneumonia and bacteremia.
Also seen is community-acquired A. baumannii pneumonia often with bacteremia and with high mortality
#Acinetobacter infections is common in #tropical countries.
Acinetobacter is a common cause of nosocomial pneumonia and bacteremia.
Also seen is community-acquired A. baumannii pneumonia often with bacteremia and with high mortality
4/
#Acinetobacter in natural disasters and war casualties.
A major cause of infection of wound, soft tissue, and invasive infections in soldiers after trauma in war zones; and in trauma victims after natural disasters, such as floods and earthquakes.
doi.org
#Acinetobacter in natural disasters and war casualties.
A major cause of infection of wound, soft tissue, and invasive infections in soldiers after trauma in war zones; and in trauma victims after natural disasters, such as floods and earthquakes.
doi.org
5/
A. baumannii is a major cause of hospital-acquired infections in ICU
Most frequent: ventilator-associated pneumonia and bloodstream infection.
Others: skin and soft-tissue infections; wound infections; urinary-tract infections; secondary meningitis.
A. baumannii is a major cause of hospital-acquired infections in ICU
Most frequent: ventilator-associated pneumonia and bloodstream infection.
Others: skin and soft-tissue infections; wound infections; urinary-tract infections; secondary meningitis.
6/
#Acinetobacter infections are associated with mechanical ventilation, intravenous and urinary catheters, surgery / invasive procedures, and prolonged broad-spectrum antimicrobials, especially in patients with burns, have trauma, or are in ICUs
#Acinetobacter infections are associated with mechanical ventilation, intravenous and urinary catheters, surgery / invasive procedures, and prolonged broad-spectrum antimicrobials, especially in patients with burns, have trauma, or are in ICUs
7/
#Acinetobacter has high frequency of an extreme drug resistance (XDR) phenotype
The resistance is mediated by all of the major resistance mechanisms: modification of target sites, enzymatic inactivation, active efflux and decreased influx of drugs
nature.com
#Acinetobacter has high frequency of an extreme drug resistance (XDR) phenotype
The resistance is mediated by all of the major resistance mechanisms: modification of target sites, enzymatic inactivation, active efflux and decreased influx of drugs
nature.com
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