DKA is a medical emergency that occurs when the body produces high levels of ketones and blood glucose levels are extremely high, leading to a severe insulin deficiency. This condition most commonly affects people with type 1 diabetes but can also occur in people with type 2 DM.
Symptoms of DKA include frequent urination, excessive thirst, dry mouth and skin, nausea and vomiting, abdominal pain, Kussmaul breathing , confusion, and fatigue. If left untreated, DKA can lead to coma and death.
DKA is caused by a lack of insulin in the body, which leads to a buildup of glucose and ketones in the bloodstream. When there's not enough insulin to move glucose into the cells, the body starts breaking down fat for energy instead, leading to the production of ketones.
To diagnose DKA, a healthcare provider will perform a physical examination, check vital signs, and order laboratory tests, including:
The goal of treatment for DKA is to correct the fluid, electrolyte, and acid-base imbalances, and bring glucose levels under control with insulin therapy. The treatment steps include:
• Insulin therapy: Insulin is given intravenously (IV) to lower blood glucose levels and stop the production of ketones.
• Fluid replacement: To correct dehydration, fluid replacement is done through IV fluids, which may also include electrolyte-rich solutions.
• Fluid replacement: To correct dehydration, fluid replacement is done through IV fluids, which may also include electrolyte-rich solutions.
To prevent DKA, people with diabetes should monitor their blood glucose levels regularly, take insulin as prescribed, eat a balanced diet, exercise regularly, and seek prompt medical attention for any signs of illness or infection.
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