My picks for the Top 10 paradigm changing advances in cancer treatment in the last 100 years.
Chronological order.
1/ Methotrexate to cure Choriocarcinoma. 1953. Roy Hertz & Min Chiu Li. First cure of solid tumors with chemo. cancer.gov
Chronological order.
1/ Methotrexate to cure Choriocarcinoma. 1953. Roy Hertz & Min Chiu Li. First cure of solid tumors with chemo. cancer.gov
2/ Cure of Acute lymphoblastic leukemia (ALL) with chemotherapy. 1958 Emil Frei, Emil Freireich, James Holland. @theNCI
The dawn of curative combination chemotherapy for cancer. @ASCO connection.asco.org
The dawn of curative combination chemotherapy for cancer. @ASCO connection.asco.org
3/ Cure of Hodgkinโs lymphoma with combination chemotherapy by @DeVitaDoctor and colleagues. @theNCI
A landmark event. A magnificent story. If you want to know more, get this book.
A landmark event. A magnificent story. If you want to know more, get this book.
4/ Cure of testicular cancer with chemotherapy. 1974. Larry Einhorn @IndianaUniv medicine.iu.edu
5/ Tamoxifen for treatment of breast cancer. 1974. V. Craig Jordan, Walpole, Richardson, Harper,
Ushered hormone therapy as treatment for cancer. (beyond the surgical approaches until then). ncbi.nlm.nih.gov
Ushered hormone therapy as treatment for cancer. (beyond the surgical approaches until then). ncbi.nlm.nih.gov
6/ Cure of diffuse large cell lymphoma with combination chemotherapy. 1975. @DeVitaDoctor and colleagues. @theNCI
This figure below, and the claim of cure made in the article, a classic, stood the test of time. @TheLancet thelancet.com
This figure below, and the claim of cure made in the article, a classic, stood the test of time. @TheLancet thelancet.com
7/ Imatinib (Gleevec) for chronic myeloid leukemia. Dramatic treatment that turned around a fatal cancer. The very essence of what targeted therapy is. 1998. Brian Druker. @nytimes nytimes.com
9/ Immunomodulatory drugs: Taking the most scorned drug ever (thalidomide) & making it into an effective cancer treatment. 1998. Bart Barlogie.
Thalidomide and itโs derivatives Revlimid & Pomlyst revolutionized treatment of myeloma. @nytimes nytimes.com
Thalidomide and itโs derivatives Revlimid & Pomlyst revolutionized treatment of myeloma. @nytimes nytimes.com
10/ CAR-T cells. Immunotherapy using the patientsโ own T cells to treat and even cure advanced cancer. 2012 Carl June. First approval 2017. @PennMedicine lancastergeneralhealth.org
Just missed the list:
Cladribine - cure of hairy cell leukemia
ATRA for acute promyelocytic leukemia
Join and add to the list!
What have I missed?
Cladribine - cure of hairy cell leukemia
ATRA for acute promyelocytic leukemia
Join and add to the list!
What have I missed?
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