#IdBoardReview Pt from Equatorial Guinea w/episodic fever, generalized rubbery lymphadenopathy (biopsy reactive) hepatosplenomegaly. CSF 10wbc & giemsa stain csf shown #idtwitter #idmeded
#Trypanosoma #brucei #gambiense +PCR in CSF & lymph node tissue
Resolution of sx post eflornithine x14 days Ref ajtmh.org
Resolution of sx post eflornithine x14 days Ref ajtmh.org
CSF exam is essential role in dx, tx selection & f/u for African #trypanosomiasis
LP at dx for stage determination & at end of tx to assess cure
presence of trypanosomes defines 2nd-stage dz
+parasite nucleic acids by PCR is useful as more sensitive approach
LP at dx for stage determination & at end of tx to assess cure
presence of trypanosomes defines 2nd-stage dz
+parasite nucleic acids by PCR is useful as more sensitive approach
# of WBC in CSF is important in both diagnostic & follow-up test
Thresholds of csf wbc≤ 5 considered cure &
csf wbc ≥ 50 considered relapse
recommended to reassess csf for response to treatment at 6 month #trypanosomiasis
Thresholds of csf wbc≤ 5 considered cure &
csf wbc ≥ 50 considered relapse
recommended to reassess csf for response to treatment at 6 month #trypanosomiasis
#trypanosoma brucei #gambiense
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