Eric Topol
Eric Topol

@EricTopol

7 Tweets 19 reads Jan 28, 2022
Brief update on Omicron, and its BA.1 and BA.2 lineages (sisters)
1. Origin—the 3 theories for how this hyper-mutated version of the virus evolved
nature.com @nature
2. A great annotated graphic by @firefoxx66 of @nextstrain conveying the antigenic distance of Omicron's BA.1 and BA.2 from prior variants
nextstrain.org
3. The BA.2 variant is spreading widely, throughout many countries in Europe and Asia, out-competing BA.1, indicating higher transmissibility. But the good news from yesterday's @UKHSA: vaccination + boost is holding up quite well; there's no indication of more immune evasion
4. Some countries where BA.2 (light purple) is making or has already made major inroads outcompeting BA.1 (purple) covariants.org
5. And there's a new thread from @trvrb covering these points and many others, with the conclusion that BA.2's impact of extending the length of time (longer tail) for the Omicron wave
7. A new BA.2 dedicated report today from @UKHSA
The secondary attack rate for BA.2 compared with BA.1 is roughly 30% increased, reflecting a transmission edge
assets.publishing.service.gov.uk
And another invaluable @kallmemeg🧵takes you through the rest of it

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