السلام عليكم 🤩..
اليوم ان شاءلله بنتكلم عن مرض (celiac disease ) ممكن مو الكل يعرف عنه بس ان شاءلله معانا اليوم توضح الصورة وتفهمونه ويكون بسيط بإذن الله 👋🏻♥️.
اليوم ان شاءلله بنتكلم عن مرض (celiac disease ) ممكن مو الكل يعرف عنه بس ان شاءلله معانا اليوم توضح الصورة وتفهمونه ويكون بسيط بإذن الله 👋🏻♥️.
اولا هوا يعتبر من
malabsorption alteration
It occurs when there is a disruption in the digestive process causing insufficient absorption of nutrients.
malabsorption alteration
It occurs when there is a disruption in the digestive process causing insufficient absorption of nutrients.
• Definition of celiac disease 💡:
is an inflammatory autoimmune condition of the small intestine, triggered by gluten in genetically susceptible individuals.
is an inflammatory autoimmune condition of the small intestine, triggered by gluten in genetically susceptible individuals.
• A gluten protein found in 💡: wheat , rye and oat .
•Clinical manifestation 💡: Anorexia, irritability, weight loss, abdominal distention, diarrhea, unabsorbed fats in the stools, osteoporosis and growth retardation.
• Diagnosis is based on a combination of symptoms, antibodies, genetic testing .
•- 1 Routine lap test /
- full blood count
- Electrolytes
- Calcium
-Vitamin B12 and Folic Prothrombin time .
- full blood count
- Electrolytes
- Calcium
-Vitamin B12 and Folic Prothrombin time .
• - 2 Serologic test /
- Tissue transglutaminase (TTG) -antibodies Antibodies against endomysium .
-Antibodies against reticulin (ARA) or gliadin (AGA)
- Tissue transglutaminase (TTG) -antibodies Antibodies against endomysium .
-Antibodies against reticulin (ARA) or gliadin (AGA)
• 3- HLA genetic type ..
• 4- Endoscopy /
Endoscopic still of duodenum of patient with celiac disease showing scalloping of folds.
Endoscopic still of duodenum of patient with celiac disease showing scalloping of folds.
• Finally treatment of celiac disease 💡/
•Presently, the only effective treatment is a life- long GLUTEN FREE DIET .
•Presently, the only effective treatment is a life- long GLUTEN FREE DIET .
• Rice, soyabean, potato and corn flour are safe
• No medication exists that will prevent damage, or prevent the body from attacking the gut when gluten is present.
• No medication exists that will prevent damage, or prevent the body from attacking the gut when gluten is present.
• Prognosis 💡:
Prognosis is excellent if properly diagnosed and treated In some patients it becomes refractory to gluten withdrawal and it carries a poor prognosis.
Prognosis is excellent if properly diagnosed and treated In some patients it becomes refractory to gluten withdrawal and it carries a poor prognosis.
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