Hairy Leukoplakia
#Dental_by_Hadeel
#Dental_by_Hadeel
🔴Definition
Hairy leukoplakia is one of the most common and characteristic lesions of human immunodeficiency virus (HIV) infection. Rarely,it can also appear in immunosuppressed patients after organ transplantation
Hairy leukoplakia is one of the most common and characteristic lesions of human immunodeficiency virus (HIV) infection. Rarely,it can also appear in immunosuppressed patients after organ transplantation
🔴Etiology
Epstein–Barr virus seems to play an important role in the pathogenesis.
Epstein–Barr virus seems to play an important role in the pathogenesis.
🔴Clinical features
presents as a white asymptomatic, often elevated and unremovable patch.The lesion is almost always found bilaterally on the lateral margins of the tongue, and may spread to the dorsumand the ventral surface.
presents as a white asymptomatic, often elevated and unremovable patch.The lesion is almost always found bilaterally on the lateral margins of the tongue, and may spread to the dorsumand the ventral surface.
Characteristically, the surface of the lesion is corrugated with a vertical orientation. However, smooth and flat lesions may also be seen. The lesion is not precancerous
🔴Laboratory tests
Histological examination, in situ hybridization, polymerase chain reaction (PCR) and electron microscopy
✳️Video about in situ hybridization: youtu.be
Histological examination, in situ hybridization, polymerase chain reaction (PCR) and electron microscopy
✳️Video about in situ hybridization: youtu.be
🔴Differential diagnosis
Chronic biting, lichen planus, frictional keratosis, cinnamon contact stomatitis, uremic stomatitis, candidiasis.
Chronic biting, lichen planus, frictional keratosis, cinnamon contact stomatitis, uremic stomatitis, candidiasis.
🔴Treatment
Not required; however, in some cases aciclovir or valaciclovir can be used with success.
Not required; however, in some cases aciclovir or valaciclovir can be used with success.
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