?BREAKING: preliminary data from an ongoing clinical study of #remdesivir showed that in 113 patients with severe #COVID19:
▶️Fever/symptoms rapidly improved
▶️Most discharged within 6 days
▶️2 died (1.8%), much less than expected for severe #COVID19
statnews.com
▶️Fever/symptoms rapidly improved
▶️Most discharged within 6 days
▶️2 died (1.8%), much less than expected for severe #COVID19
statnews.com
#Remdesivir is being studied in 2 clinical trials:
1⃣severe #COVID19 study of 2,400 patients from 152 sites all over the world
2⃣moderate #COVID19 study of 1,600 patients in 169 sites.
Results for the first 400 patients in the "severe" study are expected later this month.?
1⃣severe #COVID19 study of 2,400 patients from 152 sites all over the world
2⃣moderate #COVID19 study of 1,600 patients in 169 sites.
Results for the first 400 patients in the "severe" study are expected later this month.?
I spent nearly a decade developing the closely related #galidesivir (BCX4430, we published in @nature) that is also being tested in #COVID19 patients.
These drugs decrease viral replication by blocking the virus' ability to make new RNA.
These drugs decrease viral replication by blocking the virus' ability to make new RNA.
Another closely related drug #favipiravir that works the same way as #remdesivir and #galidesivir showed activity in a study of #COVID19 patients in #China.
There's a decent chance that 1 or more these drugs will prove effective against #coronavirus.??
There's a decent chance that 1 or more these drugs will prove effective against #coronavirus.??
One patient with a fever of 104 and shortness of breath says after 1 dose of #remdesivir, “My fever dropped almost immediately & I started to feel better."
By his 2nd dose, he was being weaned off oxygen. After 2 more doses he was discharged.
“Remdesivir was a miracle.”
By his 2nd dose, he was being weaned off oxygen. After 2 more doses he was discharged.
“Remdesivir was a miracle.”
For months, I've publicly shared my support for these drugs, because of how they work. This is *only 1* patient and does NOT prove anything. We need to see the full results of the clinical study of #remdesivir, but this preliminary report is encouraging.??
statnews.com
statnews.com
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